Research

African Woman using laptop at home at night

In addition to helping patients find the optimal therapeutic approach to their mental health concerns, we provide patients and other mental healthcare providers with resources and research to expand their knowledge of effective treatment methods and groundbreaking developments in the world of psychiatry. Explore our library of content below.

Micronutrient Therapy for Violent and Aggressive Male Youth: An Open-Label Trial Jessica L. Hambly, MPharm

In a 2016 article in the Journal of Child and Adolescent Psychopharmacology, researchers found that micronutrient therapy significantly improved parent-reported aggressive and violent behaviors. Further research is needed for additional verification but micronutrient therapy could help prevent the significant adverse events that can occur with pharmacotherapy.

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Screen Dependency Disorders: a new challenge for child neurology Aric Sigman, PhD

In a 2017 journal article, Dr. Aric Sigman found associations between screen dependency disorders and specefic neurogenetic polymorphisms, abnormal neural tissue and neural function. The research goes on to say that it is even possible that intensive routine exposure to certain screen activities during critical stages of development may alter gene expression leading to screen dependency disorders.

The article discusses these concerns and preventive strategies for child neurology.

Read the Journal Article:2017 Journal Article
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The Influence of Early Media Exposure on Children’s Development and Learning Katherine Hanson, PhD

In Dr. Katherine Hanson’s doctoral dissertation – she explores the research on early screen media exposure and its relationship to executive functioning and language skills in children. She also discusses the constant presence of television in a home and its effect on children’s working memory skills, academic ability and language outcomes.

It’s fascinating research and ties much of the modern literature on screen media and children together.

Read Her Dissertation:Dissertation Link
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What Screen Time and Screen Media Do To Your Child’s Brain and Sensory Processing Ability Amy and Evelyn Guttmann

Did you know? Night-time exposure to LED-illuminated devices (computers, tablets, phones, etc.) supress melatonin and disrupt the natural sleep cycle? Sleep cycle disruption is a significant factor in ADHD as well as other mood and behavioral problems.

Additional research also suggests that too much screen time for your children can affect the way your child’s brain functions with too much information too fast and creates more stimuli than our brains are capable of handling.

Hands on OT founders Amy and Evelyn Guttman have done a wonderful job of capturing some of this research in a recent blog post.

Read More from Amy and Emily's blog:Hands on OT
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The role of zinc supplementation on the metallothionein system in children with autism spectrum disorder Nagwa A Meguid

A recent research report suggests that children ages 3-8 on the autism spectrum may benefit from zinc supplementation. In this 2019 study, 30 patients were treated with zinc supplementation and evaluated. The data suggests an increase in cognitive-motor performance and an increase3d serum metallothionein concentration as well as a significant lowering of circulating serum levels of copper.

Read More from the National Institute of Health:Zinc Article
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Chemical Biotypes of Depression and Individualized Nutrient Therapy William J. Walsh, PhD

Is depression really only about the psychological symptoms you feel? In a study completed in May 2014, researchers found that five major depression biotypes represented roughly 95% of the 2,800 patients that were part of the research study. Those biotypes included:

  • Undermethylation 38% of patients reporting depression, anxiety, OCD tendencies, perfectionism, and a positive response to SSRI antidepressants. Undermethylation of chromatin has also been associated with excessive gene expression of SERT and increased serotonin reuptake.
  • Folate deficiency represented 20% of patients reporting high anxiety, sleep problems, food and chemical sensitivities, intolerance to SSRIs, and benefits from folate therapy or benzodiazapines.
  • 17% of depression patients exhibited elevated serum copper. Most (95%) of this group were females and had a high incidence of post-partum depression, estrogen intolerance, tinnitus, and skin sensitivity.
  • 15% of patients exhibited pyrrole disorder and reported extreme mood swings, fears, anger explosions, poor short-term memory, partial improvements from SSRIs, and benefits from zinc and B-6.
  • The smallest group 5% involved overloads of lead, mercury, or other toxic metals.

In our approach, this study emphasizes and supports the importance of advanced nutrient therapy, functional medicine, and more.

Read the Research Presentation from the Walsh InstituteWalsh Institute Presentation
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Zinc as a micronutrient in the treatment of depression Oregon State University, Micronutrient Information Center

A review of the Boston Area Community Health (BACH) survey reported higher odds of depression symptoms in women (but not in men) for those with low zinc intakes. It’s believed that zinc could (and we believe does) play a role for some individuals in preventing or alleviating depression symptoms. Two additional studies have been completed that show some therapeutic response to zinc in the treatment of depression for some adults – specifically in the first 12 weeks of treatment.

Beyond the treatment of depression, the Linus Pauling Institute’s Micronutrient Information Center has provided a great deal of research regarding the importance of Zinc as an essential mineral needed by the body for a number of functions.

Read More Information Regarding Zinc from Oregon State University's Linus Pauling Institute:Oregon State University
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